Chlorpyrifos and n-Hexane will be added to the Proposition 65 list | Synopsis and Presentations from the Developmental and Reproductive Toxicant Identification Committee Meeting Held on November 2017



A meeting of the Proposition 65[1] Developmental and Reproductive Toxicant Identification Committee (DARTIC)[2] was held on November 29, 2017, at the California Environmental Protection Agency headquarters building in Sacramento, California.  The committee considered chlorpyrifos and n-hexane for listing as known to the state to cause reproductive toxicity.

SUMMARY OF THE LISTING DECISION FOR CHLORPYRIFOS 

Chlorpyrifos will be added to the Proposition 65 list of chemicals known to the state to cause reproductive toxicity based on the developmental endpoint. 

All eight DARTIC members in attendance voted that chlorpyrifos “has been clearly shown through scientifically valid testing according to generally accepted principles to cause developmental toxicity.” (This was the only endpoint considered by the DARTIC at this meeting.) Six “yes” votes were needed to add chlorpyrifos to the list.

SUMMARY OF THE LISTING DECISION FOR N-HEXANE

n-hexane will be added to the Proposition 65 list of chemicals known to the state to cause reproductive toxicity based on the male reproductive endpoint. 

In voting on whether n-hexane “has been clearly shown through scientifically valid testing according to generally accepted principles to cause reproductive toxicity,” the nine DARTIC members in attendance made the following determinations:

  • For the male reproductive toxicity endpoint, six members voted yes, two voted no, and one abstained. Six “yes” votes were needed to add n-hexane to the list for this endpoint.
  • For the female reproductive toxicity endpoint, all nine members in attendance voted no. 
  • For the developmental toxicity endpoint, three members voted yes, and six members voted no.

CONTINUE READING ON oehha.ca.gov
                   

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