OECD | Draft Guidance Document for the scientific review of Adverse Outcome Pathways


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The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and cellular events that lead from exposure to a stressor to adverse effects, and to identify critical data gaps in the understanding of those pathways.

Link to the OECD | Draft Guidance Document for the scientific review of Adverse Outcome Pathways

                   

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