- December 13, 2020
OECD | Draft Guidance Document for the scientific review of Adverse Outcome Pathways
The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of
mechanistic information derived from toxicological science in a structured manner, to assist in
establishing causal relationships between molecular and cellular events that lead from exposure to a
stressor to adverse effects, and to identify critical data gaps in the understanding of those pathways.
Link to the OECD | Draft Guidance Document for the scientific review of Adverse Outcome Pathways