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IARC | Volume 136: Talc and acrylonitrile

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The International Agency for Research on Cancer (IARC) has published the results of its latest evaluation on the carcinogenicity of talc and acrylonitrile in The Lancet Oncology. This evaluation was conducted during IARC Monographs Meeting 136.

Acrylonitrile, a high-production chemical used in manufacturing fibers, resins, synthetic rubber, and plastics, poses occupational exposure risks primarily through inhalation and skin contact, especially in production industries. Tobacco smoke is the main source of exposure for the general population.

Talc, a hydrated magnesium silicate used in various industries and consumer products, also poses occupational exposure risks mainly during mining and milling. The general population can be exposed to talc through products like body powders, with potential exposure pathways including ingestion, inhalation, and skin contact.

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