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ECHA has begun testing for hazard endpoints of 42 substances
| Substance name | EC Number | Hazard endpoint for which vertebrate testing was proposed |
| 3-chloropropyl)dimethoxymethylsilane | 242-056-0 | Sub-chronic toxicity (90-day): oral |
| (R)-p-mentha-1,8-diene | 227-813-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) |
| 1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters | 701-339-3 | Reproductive toxicity (pre-natal developmental toxicity) |
| 1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate | 931-295-2 | Sub-chronic toxicity (90-day): oral |
| 1,4-dimethylpiperazine | 203-412-0 | Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
| 4-acetyl-2-[(acetyloxy)methyl]phenyl acetate | 921-042-4 | Genetic toxicity in vivo |
1-ethoxy-2-(2-methoxyethoxy)ethane | 213-690-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
| 202-888-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) | |
| 2,3-epoxypropyl neodecanoate | 247-979-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
| 2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) |
| 2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) |
| 2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate | 239-701-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral |
| 4,4''-isopropylidenedi-o-cresol | 201-240-0 | Genetic toxicity in vivo |
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” |
| Ashes (residues), nonhazardous municipal solid waste | 937-417-0 | Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
| choline hydroxide | 204-625-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) |
| dichlorobis(?-cyclopentadienyl)titanium | 215-035-9 | Genetic toxicity in vivo |
| dimethoxymethylsilane | 240-914-9 | Sub-chronic toxicity (90-day): oral |
dipotassium bis[µ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer | 234-293-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
| 265-183-3 | Genetic toxicity in vivo | |
| Distillates (petroleum), hydrotreated middle | 265-148-2 | Genetic toxicity in vivo |
| Gas oils (petroleum), hydrodesulfurized | 265-182-8 | Genetic toxicity in vivo |
| hexadecyltrimethoxysilane | 240-464-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) |
| Lithium phosphorodifluoridate | 643-080-8 | Reproductive toxicity (pre-natal developmental toxicity) |
| lithium tetrafluoroborate, anhydrous | 238-178-9 | Genetic toxicity in vivo |
| 435-860-1 | Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral | |
| N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-ß-alanine | 264-761-2 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. |
| 217-126-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. | |
| Phosphoric acid, 2-ethylhexyl ester | 235-741-0 | Reproductive toxicity (pre-natal developmental toxicity) |
| Platinum(IV) aqua hydroxo nitrato complexes | 701-319-4 | Genetic toxicity in vivo |
| Platinum,1,3-diethenyl-1,1,3,3- tetramethyldisiloxane and its platinum(0) complexes | 701-315-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. |
| Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane | 915-748-1 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) |
| Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate | 911-616-2 | Sub-chronic toxicity (90-day): oral |
| sodium 1-hydroxyethanesulphonate | 213-037-4 | Genetic toxicity in vivo |
| triethoxy(methyl)silane | 217-983-9 | Sub-chronic toxicity (90-day): oral |
| 246-148-1 | Genetic toxicity in vivo |
Link to the Hazard Endpoint Testing
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