Canada | Phenacetin identified for action under the Chemicals Management Plan (CMP)

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Pursuant to section 74 of the Canadian Environmental Protection Act, 1999 (CEPA) (Canada 1999), the Minister of Environment and the Minister of Health have conducted a screening assessment of acetamide, N-(4-ethoxyphenyl)-(herein referred to as phenacetin phenacetin).  This substance was identified as a priority for assessment under Canada’s Chemicals Management Plan (CMP), because it met categorization criteria under subsection 73(1) of CEPA (ECCC, HC [modified 2007]).

The ecological risk of phenacetin was characterized using the Ecological Risk Classification of organic substances (ERC) (ECCC 2016a). The ERC describes the hazard of a substance using key metrics including mode of action, chemical reactivity, food-web derived internal toxicity, bioavailability, and chemical and biological activity and considers the possible exposure of organisms in the aquatic and terrestrial environments based on factors including potential emission rates, overall persistence and long-range transport potential in air. The various lines of evidence are combined to identify substances as warranting further evaluation of their potential to cause harm to the environment or as having a low likelihood of causing harm to the environment.



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