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The Minutes of the 61st Meeting of the Committee for Risk Assessment (RAC-61) includes the following item(s) for discussion:
CLH dossiers
1. Hazard classes for agreement without plenary debate (A-list)
1. 7-oxabicyclo[4.1.0]hept-3-ylmethyl 7-oxabicyclo[4.1.0]heptane-3-carboxylate (EC 219-207-4; CAS 2386-87-0): Skin sensitisation, mutagenicity, STOT RE
2. Tetrasodium 4-amino-5-hydroxy-3,6-bis[[4-[[2- (sulphonatooxy)ethyl]sulphonyl] phenyl]azo]naphthalene-2,7-disulphonate; [1] and Reaction products of 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid, coupled twice with diazotized 2-[(4-aminophenyl)sulfonyl]ethyl hydrogen sulfate, sodium salts; [2] and disodium 4-amino-5-hydroxy-3,6-bis{[4- (vinylsulfonyl)phenyl]diazenyl}naphthalene-2,7-disulfonate; [3] (EC 241-164-5 [1], - [2], - [3]; CAS 17095-24-8 [1], - [2], 100556-82-9 [3]): Respiratory sensitisation, skin sensitisation
3. 2-(dimethylamino)-2-[(4-methylphenyl)methyl]-1-[4-(morpholin-4- yl)phenyl]butan-1-one (EC 438-340-0; CAS 119344-86-4): Reproductive toxicity, STOT RE, hazardous to the aquatic environment
4. Formic acid ... % (EC 200-579-1; CAS 64-18-6): Physical hazards, acute oral and inhalation toxicity, serious eye damage/eye irritation
5. Glyphosate (EC 213-997-4, CAS 1071-83-6): Physical hazards, acute toxicity via all routes, skin corrosion/irritation, serious eye damage/eye irritation, respiratory sensitisation, skin sensitisation, STOT SE, STOT RE
6. Dicamba (ISO); 2,5-dichloro-6-methoxybenzoic acid; 3,6-dichloro-2- methoxybenzoic acid (EC 217-635-6; CAS 1918-00-9): Acute toxicity via all routes, skin corrosion/irritation, serious eye damage/eye irritation, skin sensitisation, STOT SE, STOT RE, mutagenicity, reproductive toxicity, hazardous to the aquatic environment, hazardous to the ozone layer
7. Peracetic acid … % (EC 201-186-8; CAS 79-21-0): Flammable liquid, acute toxicity via all routes, hazardous to the aquatic environment
8. Formaldehyde … % (EC 200-001-8; CAS 50-00-0): Physical hazards, acute oral and inhalation toxicity, skin sensitisation
9. S-metolachlor (ISO); 2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(2S)-1- methoxypropan-2-yl]acetamide; (RaSa)-2-chloro-N-(6-ethyl-o-tolyl)-N-[(1S)-2- methoxy-1-methylethyl]acetamide [contains 80-100 % 2-chloro-N-(2-ethyl-6- methylphenyl)-N-[(2S)-1-methoxypropan-2-yl]acetamide and 0-20 % 2-chloroN-(2-ethyl-6-methylphenyl)-N-[(2R)-1-methoxypropan-2-yl]acetamide] (EC -; CAS 87392-12-9): Mutagenicity, STOT RE, reproductive toxicity, hazardous to the aquatic environment
10. Silver (EC 231-131-3; CAS 7440-22-4): Carcinogenicity
2. Substances with hazard classes for agreement in plenary session
1. Glyphosate (EC 213-997-4, CAS 1071-83-6): Mutagenicity, carcinogenicity, hazardous to the aquatic environment
2. Dicamba (ISO); 2,5-dichloro-6-methoxybenzoic acid; 3,6-dichloro-2- methoxybenzoic acid (EC 217-635-6; CAS 1918-00-9): Physical hazards, carcinogenicity
3. Peracetic acid … % (EC 201-186-8; CAS 79-21-0): Organic peroxide
4. Formaldehyde … % (EC 200-001-8; CAS 50-00-0): Acute dermal toxicity
5. S-metolachlor (ISO); 2-chloro-N-(2-ethyl-6-methylphenyl)-N-[(2S)-1- methoxypropan-2-yl]acetamide; (RaSa)-2-chloro-N-(6-ethyl-o-tolyl)-N-[(1S)-2- methoxy-1-methylethyl]acetamide [contains 80-100 % 2-chloro-N-(2-ethyl-6- methylphenyl)-N-[(2S)-1-methoxypropan-2-yl]acetamide and 0-20 % 2-chloroN-(2-ethyl-6-methylphenyl)-N-[(2R)-1-methoxypropan-2-yl]acetamide] (EC -; CAS 87392-12-9): Carcinogenicity
6. Silver (EC 231-131-3; CAS 7440-22-4): STOT RE, reproductive toxicityRestriction Annex XV dossiers
Conformity check and key issues discussion
1. Creosote and Creosote related substances
3. N,N-dimethylacetamide and 1-ethylpyrrolidin-2-one
Opinion development
1. Per- and polyfluoroalkyl substances (PFASs) in fire-fighting foams – First draft opinion
2. Substances containing polycyclic aromatic hydrocarbons (PAHs) in clay targets for shooting – second draft opinion
3. 2,4-dinitrotoluene – third draft opinion
4. Lead and its compounds in outdoor shooting and fishing – fifth draft opinion
Link to the Minutes of the 61st Meeting of the Committee for Risk Assessment (RAC-61)
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