Cadmium Body Burden and Gestational Diabetes Mellitus: A Prospective Study

Background - Several studies have reported that cadmium (Cd) is associated with type 2 diabetes. However, little is known about Cd exposure and the risk of gestational diabetes mellitus (GDM).

Objectives - We examined the association between Cd body burden in early pregnancy and the risk of GDM.

Conclusions - To our knowledge, this is the first report of an association between urinary Cd levels in early pregnancy and GDM. Our findings suggest that Cd body burden increases the risk of GDM and that the association may be modified by fetal sex. 

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