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The 1st Watch List (WL) was established by the Commission Implementing Decision (EU) 2015/4951 in March 2015. The list was updated in June 2018 by the Commission Implementing Decision (EU) 2018/840. During the WL update, the Commission concluded that the substances diclofenac, oxadiazon, 2,6-di-tert-butyl-4-methylphenol, tri-allate and 2-ethylhexyl 4-methoxycinnamate should be removed from the WL, while the insecticide metaflumizone and the antibiotics amoxicillin and ciprofloxacin should be included (EU 2018/840). The purpose of this report is to propose candidate substances for the 3rd WL. Three pillars of information were used to select the candidate substances. The first pillar is the outcome of the last prioritisation exercise , the second includes the outcome of the review of the 1st WL and recommendations for the 3rd WL, and the third is based on a literature search and/or other sources (for instance information from MS).
The selection of candidate substances took into consideration their hazard properties as well as the availability of reliable safety threshold (including the contribution to the antimicrobial resistances for antibiotics) and the availability of relevant analytical methods for monitoring in the appropriate environmental matrix. Following the Working Group Chemicals meeting, held on 15-16 January 2020, comments and information received by the MS and Stakeholders regarding the proposed candidate substances were taken into account. The candidate substances, fulfilling the selection criteria and identified by the JRC as most suitable for inclusion in the next WL include two antibiotics, which are prescribed together to overcome to the resistance. Ten fungicides, the azole substances either pharma or pesticides, to investigate their contribution to the antimicrobial resistance, an anti-depressant pharmaceutical and its metabolite. Two additional fungicides were also included since widely used as pesticides.
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