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ECHA has launched 28 new consultations on testing proposals. The deadline for comments is 3 August 2020:
| Name | EC Number | CAS Number | Hazard endpoint for which vertebrate testing was proposed |
4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane | 240-212-2 | 16068-37-4 | Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity) |
| 241-881-3 | 17955-88-3 | Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) | |
4,4''-(9H-fluoren-9-ylidene)bis(2-chloroaniline) | 407-560-9 | - | Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
bis(trimethoxysilylpropyl)amine | 280-084-5 | 82985-35-1 | Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity |
| 205-492-2 | 141-63-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) | |
| 2,2''-azobis[4-methoxy-2,4-dimethylvaleronitrile] | 239-593-8 | 15545-97-8 | Genetic toxicity in vivo |
| 204-884-0 | 128-39-2 | Reproductive toxicity (pre-natal developmental toxicity) | |
| 241-367-9 | 17345-61-8 | Genetic toxicity in vivo | |
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane | 219-784-2 | 2530-83-8 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant |
| 231-784-4 | 7727-43-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1) | |
| 203-338-9 | 105-85-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | |
| Dimethyl 2,2''-azobis(2-methylpropionate) | 219-976-6 | 2589-57-3 | Genetic toxicity in vivo |
| Linalyl acetate | 204-116-4 | 115-95-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) |
| Maleic acid | 203-742-5 | 110-16-7 | Reproductive toxicity (pre-natal developmental toxicity) |
N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate | 247-161-5 | 25646-71-3 | Genetic toxicity in vivo |
| 217-565-6 | 1888-91-1 | Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant | |
| 250-465-0 | 31098-20-1 | Genetic toxicity in vivo | |
| 208-047-0 | 506-61-6 | Genetic toxicity in vivo | |
| 237-748-4 | 13967-50-5 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | |
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 911-381-6 | - | Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant |
| Reaction mass of disodium (sulphonatothio)acetate and sodium chloride | 947-115-0 | - | Genetic toxicity in vivo |
Link to the ECHA | Testing proposals
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