ECHA has launched 28 new consultations on testing proposals | Deadline for comments 3 August 2020



ECHA has launched 28 new consultations on testing proposals. The deadline for comments is 3 August 2020:

NameEC NumberCAS NumberHazard endpoint for which vertebrate testing was proposed

4,4,7,7-tetraethoxy-3,8-dioxa-4,7-disiladecane 


240-212-216068-37-4Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)

1,1,1,3,5,5,5-heptamethyl-3-octyltrisiloxane 

241-881-317955-88-3Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)

4,4''-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 


407-560-9-Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)

bis(trimethoxysilylpropyl)amine 


280-084-582985-35-1Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity

dodecamethylpentasiloxane 


205-492-2141-63-9Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
2,2''-azobis[4-methoxy-2,4-dimethylvaleronitrile] 239-593-815545-97-8Genetic toxicity in vivo

2,6-di-tert-butylphenol 


204-884-0128-39-2Reproductive toxicity (pre-natal developmental toxicity)

3,4-dihydroxybenzonitrile 

241-367-917345-61-8Genetic toxicity in vivo

[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 


219-784-22530-83-8Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant

Barium sulfate 

231-784-47727-43-7Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1)

Citronellyl formate 

203-338-9105-85-1Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
Dimethyl 2,2''-azobis(2-methylpropionate)219-976-62589-57-3Genetic toxicity in vivo
Linalyl acetate 204-116-4115-95-7Reproductive toxicity (extended one-generation reproductive toxicity study)
Maleic acid 203-742-5110-16-7Reproductive toxicity (pre-natal developmental toxicity)

N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate 

247-161-525646-71-3Genetic toxicity in vivo

N-acetylhexanelactam 

217-565-61888-91-1Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant

Potassium 3-sulphonatopropyl acrylate 

250-465-031098-20-1Genetic toxicity in vivo

Potassium dicyanoargentate 


208-047-0506-61-6Genetic toxicity in vivo

Potassium dicyanoaurate 


237-748-413967-50-5Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant

Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane

911-381-6-Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant
Reaction mass of disodium (sulphonatothio)acetate and sodium chloride947-115-0-Genetic toxicity in vivo

Link to the ECHA | Testing proposals

                   

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