In their September 18, 2023 blog post titled "Now's the Time — How EPA Can Use TSCA to Turn Off the PFAS Tap," the Environmental Defense Fund (EDF) outlines key recommendations for the U.S. Environmental Protection Agency (EPA) regarding per- and polyfluoroalkyl substances (PFAS). EDF advises the EPA to employ the best available science, including expertise from agencies like the Integrated Risk Information System (IRIS), to inform decisions, particularly in setting drinking water standards based on robust scientific findings. They urge a shift from evaluating PFAS chemicals in isolation to adopting a cumulative risk assessment model, considering the combined effects of exposure, especially for vulnerable populations. EDF disputes the notion of negligible PFAS releases, emphasizing the environmental mobility and bioaccumulative nature of PFAS. They propose that using the Toxic Substances Control Act (TSCA) to restrict or ban PFAS would encourage the development and adoption of safer alternatives. In conclusion, EDF believes that by utilizing its full TSCA authority, the EPA can safeguard a future where chemicals, notably PFAS, do not compromise public health and safety.