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This OECD project aims to contribute to the discussion on a ‘Safe(r) Innovation Approach’ for more sustainable nanomaterials and nano-enabled products. The document presents common working descriptions to ensure a common understanding of concepts such as: Safe(r) Innovation Approach and its elements, Safe(r)-by-Design and Regulatory Preparedness. Then the document compiles existing risk assessment tools, frameworks and initiatives developed for Safe(r)-by-Design. The inventory of risk assessment tools and frameworks should contribute in assisting industry to implement a 'Safe(r) Innovation Approach' for NMs and nano-enabled products. This includes a review of lessons learned from applying existing Safe(r)-by-Design concepts and tools and methods applied in hazard, exposure and risk assessment and management along the innovation value chain. A review of the applicability of the Safe(r)-by-Design concept, based on feedback gained through case studies and existing initiatives was conducted. The constraints and limitations on the applicability of these tools and frameworks were analysed.
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