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EFSA's Scientific Committee has launched an open consultation on its draft EFSA Scientific Committee Opinion on biological plausibility of non-monotonic dose responses and their impact on the risk assessment. This document assesses the biological relevance of the apparent non-monotonic dose-responses identified in the external report produced under GP/EFSA/SCER/2014/01, focusing on the in vivo datasets fulfilling most of the checkpoints of the visual/statistics-based analysis.
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