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Growing large crystals (>0.1mm3) of biological macromolecules that are suitable for neutron crystallography is not an easy task. The solution to this problem holds the key to overcoming the single biggest difficulty that limits the technique and would have a major impact on the range of biological problems that could be addressed using neutron protein crystallography. What if there was a way to arrange many microcrystals so that they behave as if they were a large crystal?
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